Yeast Metabolites for Cell Culture

ART-YD-017 is a yeast metabolite complex designed for use as a nutritional supplement in biopharma cell culture workflows and microbial fermentation. It is produced from selected yeast biomass through controlled autolysis or hydrolysis, followed by clarification, concentration, drying, and sieving. The resulting free-flowing powder delivers soluble nitrogen, short-chain peptides, amino acids, nucleotides, B-group vitamin fractions, trace minerals, and endogenous yeast metabolites that can support robust media development and process consistency.

Typical specification targets may include moisture not more than 6.0%, total nitrogen 7.0-10.0%, amino nitrogen 2.0-4.5%, protein equivalent 40-60%, ash 8-15%, pH 5.0-7.0 in 2% solution, and particle size through 60-80 mesh, depending on lot and grade. The product is intended for R&D screening, pilot fermentation, and production media optimization by qualified industrial users. For related yeast-derived inputs, see the yeast derivatives for biotech category.

• Biopharma cell culture media development: Used as a non-animal nutrient component in screening studies for cell growth, productivity, and process robustness in controlled laboratory and production environments.
• Microbial fermentation: Supplies organic nitrogen, peptides, vitamins, and minerals for bacteria, yeast, and filamentous organism processes where defined or semi-defined nutrient systems are being evaluated.
• Process scale-up: Supports transfer from shake flask to bench, pilot, and production fermenters when lot documentation, pack integrity, and reproducible nutrient contribution are procurement priorities.
• R&D formulation work: Suitable for comparison against yeast extract, peptone, hydrolysate, and other fermentation nutrients in design-of-experiment programs.
• Industrial biotechnology: Applicable in enzyme expression, recombinant protein workflows, starter culture propagation, and metabolite production where a consistent yeast-based matrix is specified.

ArtemisYeast supplies ART-YD-017 on an inquiry-only basis. Procurement teams can request a bulk quote with target application, annual volume, destination country, documentation requirements, and any preferred technical limits for review.

Store unopened 20 kg multi-wall sacks in a cool, dry, well-ventilated warehouse away from direct sunlight, moisture, strong odors, and reactive chemicals. Recommended storage is below 25°C with relative humidity controlled where possible. Under recommended conditions, the typical shelf life is 24 months from manufacture, subject to the certificate of analysis and regional stock rotation.

After opening, reseal the inner liner tightly and use promptly to reduce moisture uptake and microbiological risk. Operators should follow standard dry powder handling controls, including dust minimization, local exhaust where required, and appropriate personal protective equipment. Use clean, dry scoops and avoid cross-contact with allergen, animal-derived, or incompatible raw materials if the material is being evaluated for controlled media systems.

ART-YD-017 is supplied with lot-based quality documentation for B2B qualification. A certificate of analysis can include appearance, moisture, nitrogen parameters, pH, ash, particle size, microbiological limits, and other agreed parameters. Typical microbiological controls may include total plate count, yeast and mold, coliforms, and absence testing for selected pathogens as specified for the grade and destination market.

Manufacturing documentation may be available on request for HACCP-aligned production, ISO 22000, FSSC 22000, Halal, Kosher, food-grade declaration, non-animal origin statement, GMO status statement, allergen statement, heavy metal limits, residual solvent statement, and material safety information, depending on the selected lot and supply route. For document review and supplier qualification, visit quality and documentation. This product is a process ingredient for qualified industrial use and should be evaluated by the buyer in its own media formulation, production system, and regulatory context.